In Kyusho understanding the anatomy is only a small step, understanding the physiology is far more important and profound.
We all understand now that attacking the inner human is far more efficient with more potent affect. However that is just step one as understanding how and what you are affecting, but more importantly how to take that information to make every aspect of your martial art better.
Tuite or Joint Manipulation methods are inherent in all styles, but it is not simply to control or destroy a joint, it has far greater meaning and is quintessential to the martial arts.
Tuite attacks the autonomic nervous system and it does that because all the joints are attached by muscles, tendons and ligaments.